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Comments from the users:
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Dr. G.
T. Krishnamurthy said that while ultrasound, computed tomography
(CT) and magnetic resonance imaging (MRI)
are the primary imaging procedures used to detect such diseases, their
results are limited in providing functional assessment.
“Although CT and MRI provide excellent morphologic information, they
depend upon change in the form and
structure of the organs to detect diseases,” he said. “The
KHBS will help clinicians detect the earliest
manifestations of liver diseases by identifying functional changes
at the cellular level, increasing the chances
of complete recovery.”
Gallbladder functional changes also occur many years prior to the
development of gallstones. But
measurement of gallbladder functions (ejection fraction) have been
hampered by the lack of reliable, widely
available, validated, and FDA-approved software.
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“Because of the non-availability of reliable hepatobiliary software,
there is no universal standard in data collection
and analysis to compare results from one center to another,” said Dr.
S. Krishnamurthy.
She added that until the FDA approved KHBS, many centers published study
results using “homemade”
software that was not available for others to use.
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For the
first time, nuclear-medicine departments will have access to universal
standardization in liver
and gallbladder functional
imaging. "The availability
of this rigorous quantitative tool will help the
entire field and is long overdue," according to Dr. Sanjiv Sam
Gambhir, chief of the nuclear medicine
division and professor of radiology at the Stanford University School of
Medicine and director of Stanford's
molecular imaging program.
- “This software package allows doctors to interpret
the studies exactly the same way, whether in California
or Alaska,” added Christiaan Schiepers, M.D., Ph.D., nuclear
medicine specialist, University of California
Los Angeles Medical Center (UCLA), and editor of the textbook,
Diagnostic Nuclear Medicine.
“A patient can be diagnosed as having a certain liver or gallbladder
disease by comparing their test results
to the normal database.”
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